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Steroid And Juvenille Arthritis Aren't Common |
By:
Jerry Gilders |
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In the past, Methotrexate was very common when talking about polyarticular diseases including juvenile rheumatoid arthritis. It was used only when the patient did not respond to other medications and was more used in adult patients suffering from rheumatoid arthritis. Metrotrexate was used in weekly therapy and showed efficacy after around 2 months. The problem is that there appears to be low toxicity when measured in connection with juvenile rheumatoid arthritis. You can notice a reduction in systemic features and a reduction in the need for corticosteroids but toxicity levels need to be measured in patients suffering from juvenile rheumatoid arthritis.
There are a number of immuno-suppressant drugs that are also used in treatment. This includes Alkylating and Azathioprine and different agents like Chlorambucil and Cyclophosphamide. The problem is that there is an association between these with amenorrhea and sterility. In most cases they will be utilized as adjunctive therapy in steroid toxic children and when dealing with systemic diseases that show life threatening complications or severe progressive erosive arthritis.
Steroid toxic and juvenile rheumatoid arthritis is a topic that needs to be addressed with the maximum of seriousness. When dealing with children you need to realize that they do not have the same body characteristics as adults and this is why the condition is far more damaging. If you suspect that your child is suffering from the disease be sure to consult a specialist as soon as possible.
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Article Source: http://www.statssheet.com/articles/article72612.html |
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